Eukaryotic Translation Initiation Factor 6 (EIF6) Antibody
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Catalogue No: abx001502
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US$348.00
(Size: 60 µl)
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Datasheet SDS
EIF6 Antibody is a Rabbit Polyclonal antibody against EIF6. Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
Research Articles on Eukaryotic Translation Initiation Factor 6 (EIF6)
| Target | Eukaryotic Translation Initiation Factor 6 (EIF6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human EIF6 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P56537 (UniProt, ExPASy) |
| UniProt Secondary AC | B7ZBG9, Q6IBN8, Q96TD5 |
| UniProt Entry Name | IF6_HUMAN |
| Gene Symbol | EIF6 |
| GeneID | 3692 |
| NCBI Accession | NP_852133.1 |
| KEGG | hsa:3692 |
| String | 9606.ENSP00000363574 |
| Molecular Weight | Calculated MW: 23 kDa/26 kDa Observed MW: 27 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
