Zinc Phosphodiesterase ELAC Protein 2 (ELAC2) Antibody

ELAC2 Antibody is a Rabbit Polyclonal antibody against ELAC2. The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Zinc Phosphodiesterase ELAC Protein 2 (ELAC2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ELAC2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BQ52 (UniProt, ExPASy)
UniProt Secondary AC	B4DPL9, Q6IA94, Q9HAS8, Q9HAS9, Q9NVT1
UniProt Entry Name	RNZ2_HUMAN
Gene Symbol	ELAC2
GeneID	60528
NCBI Accession	NP_776065.1
String	9606.ENSP00000337445
Molecular Weight	Calculated MW: 92 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Zinc Phosphodiesterase ELAC Protein 2 (ELAC2)

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