Homeobox Protein Engrailed-2 (EN2) Antibody

EN2 is thought to have a role in controlling development. In Drosophila, the protein plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. This protein has been implicated in the control of pattern formation during development of the central nervous system.

Target	Homeobox Protein Engrailed-2 (EN2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human EN2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P19622 (UniProt, ExPASy)
UniProt Secondary AC	A4D252, Q549U3, Q9UD58
UniProt Entry Name	HME2_HUMAN
Gene Symbol	EN2
KEGG	hsa:2020
String	9606.ENSP00000297375
Molecular Weight	Calculated MW: 34.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Homeobox Protein Engrailed-2 (EN2)

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