Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Antibody
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Catalogue No: abx031190
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
Research Articles on Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1)
| Target | Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P22413 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3 |
| UniProt Entry Name | ENPP1_HUMAN |
| Gene Symbol | ENPP1 |
| KEGG | hsa:5167 |
| String | 9606.ENSP00000354238 |
| Molecular Weight | Calculated MW: 105 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |