EPH Receptor A4 (EPHB4) Antibody

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Target	EPH Receptor A4 (EPHB4)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of EphB4 expressed in E. coli.
Isotype	IgG2a
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P54760 (UniProt, ExPASy)
UniProt Secondary AC	B5A970, B5A971, B5A972, Q7Z635, Q9BTA5, Q9BXP0
UniProt Entry Name	EPHB4_HUMAN
Gene Symbol	EPHB4
GeneID	2050
OMIM	600011
HGNC	3395
KEGG	hsa:2050
Ensembl	ENSG00000196411
String	9606.ENSP00000350896
Enzyme Commission Number	EC 2.7.10.1 EC 2.7.1.112
Molecular Weight	108 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on EPH Receptor A4 (EPHB4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue