EPH Receptor A4 (EPHB4) Antibody
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Catalogue No: abx010727
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Research Articles on EPH Receptor A4 (EPHB4)
| Target | EPH Receptor A4 (EPHB4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of EphB4 expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P54760 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A970, B5A971, B5A972, Q7Z635, Q9BTA5, Q9BXP0 |
| UniProt Entry Name | EPHB4_HUMAN |
| Gene Symbol | EPHB4 |
| GeneID | 2050 |
| OMIM | 600011 |
| HGNC | 3395 |
| KEGG | hsa:2050 |
| Ensembl | ENSG00000196411 |
| String | 9606.ENSP00000350896 |
| Enzyme Commission Number | EC 2.7.10.1 EC 2.7.1.112 |
| Molecular Weight | 108 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |