Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) Antibody
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Catalogue No: abx033909
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Upon binding to EGF receptor, EPS8 enhances EGF-dependent mitogenic signals. It can bind multiple cellular targets. EPS8 is expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. It is expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells. EPS8 is phosphorylated by several receptor tyrosine kinases. The protein contains 1 PH domain and 1 SH3 domain.
Research Articles on Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8)
| Target | Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human EPS8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q12929 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NMC3, A8K6W2, A8KA66, B4DX66, Q8N6J0 |
| UniProt Entry Name | EPS8_HUMAN |
| NCBI Accession | NP_004438.3 |
| KEGG | hsa:2059 |
| String | 9606.ENSP00000281172 |
| Molecular Weight | Calculated MW: 91.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |