V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) Antibody
REQUEST MORE INFO
Catalogue No: abx033547
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors.
Research Articles on V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3)
| Target | V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ERBB3) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human ERBB3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P21860 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K6L6, B4DIK7, B4DV32, E9PDT8, Q9BUD7 |
| UniProt Entry Name | ERBB3_HUMAN |
| NCBI Accession | NP_001005915.1 NP_001973.2 |
| KEGG | hsa:2065 |
| String | 9606.ENSP00000267101 |
| Molecular Weight | Calculated MW: 148 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |