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General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2) Antibody
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Catalogue No: abx004312
Price:
US$348.00
(Size: 60 µl)
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ERCC2 Antibody is a Rabbit Polyclonal antibody against ERCC2. The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2)
| Target | General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ERCC2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P18074 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2TB78, Q2YDY2, Q7KZU6, Q8N721 |
| UniProt Entry Name | ERCC2_HUMAN |
| Gene Symbol | ERCC2 |
| GeneID | 2068 |
| NCBI Accession | NP_001124339.1 |
| KEGG | hsa:2068 |
| String | 9606.ENSP00000375809 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
