General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2) Antibody

REQUEST MORE INFO
Catalogue No: abx004312
Price: US$203.00
(Size: 20 µl)

Click on the image to see the image legend

Available Options

* Size:




Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
ERCC2 Antibody is a Rabbit Polyclonal antibody against ERCC2. The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human XPD/XPD/ERCC2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18074 (UniProt, ExPASy)
UniProt Secondary AC Q2TB78, Q2YDY2, Q7KZU6, Q8N721
UniProt Entry Name ERCC2_HUMAN
Gene Symbol ERCC2
GeneID 2068
NCBI Accession NP_001124339.1
KEGG hsa:2068
String 9606.ENSP00000375809
Molecular Weight Calculated MW: 87 kDa
Observed MW: 87 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on General Transcription And DNA Repair Factor IIH Helicase Subunit XPD (ERCC2)


Write a review

Tags:
(Click to show)