Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody

Catalogue No: abx000517
Price: £40.00
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Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody

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Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody is a Rabbit Polyclonal antibody against Erk1 (pT202/Y204) / Erk2 (pT185/Y187) . The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Target Erk1 (pT202/Y204) / Erk2 (pT185/Y187)
Reactivity Human
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T202/Y204 of human Erk1/2.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 42 kDa - 44 kDa
Swiss Prot P27361
GeneID 5594/5595
Gene Symbol MAPK1, MAPK3
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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