Erk1 (pT202 / Y204) / Erk2 (pT185 / Y187) Antibody

Catalogue No: abx000517
Price: £120.00
(Size: 20 µl)
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Erk1 (pT202/Y204) / Erk2 (pT185/Y187) Antibody is a Rabbit Polyclonal antibody against Erk1 (pT202/Y204) / Erk2 (pT185/Y187). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Target Erk1 (pT202/Y204) / Erk2 (pT185/Y187)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T202/Y204 of human Erk1/2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P28482 (UniProt, ExPASy) P27361 (UniProt, ExPASy)
UniProt Secondary AC A8CZ58, B0LPG3, Q8NHX1
UniProt Entry Name MK03_HUMAN
Gene Symbol MAPK1, MAPK3
GeneID 5594/5595
String 9606.ENSP00000263025
Molecular Weight Calculated MW: 36 kDa, 41 kDa, 38 kDa, 40 kDa, 43 kDa
Observed MW: 38 kDa, 41 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Erk1 (pT202/Y204) / Erk2 (pT185/Y187)

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