Estrogen Receptor (ESR1) Antibody

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Catalogue No: abx000676
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
ESR1 Antibody is a Rabbit Polyclonal antibody against ESR1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Target Estrogen Receptor (ESR1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence within amino acids 516-595 of human ESRα.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P03372 (UniProt, ExPASy)
UniProt Secondary AC Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7
UniProt Entry Name ESR1_HUMAN
Gene Symbol ESR1
GeneID 2099
NCBI Accession NP_000116.2
KEGG hsa:2099
String 9606.ENSP00000405330
Molecular Weight Calculated MW: 66 kDa
Observed MW: 66 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration 3.64 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Estrogen Receptor (ESR1)


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