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ESR1 (pS106) Antibody

Catalogue No: abx000395
Price: £220.00
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ESR1 (pS106) Antibody ESR1 (pS106) Antibody

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ESR1 (pS106) Antibody is a Rabbit Polyclonal antibody against ESR1 (pS106). This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Target ESR1 (pS106)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S106 of human ESR1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P03372 (UniProt, ExPASy)
UniProt Secondary AC Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7
UniProt Entry Name ESR1_HUMAN
Gene Symbol ESR1
GeneID 2099
KEGG hsa:209
String 9606.ENSP00000405330
Molecular Weight Calculated MW: 35 kDa, 47 kDa, 53 kDa, 66 kDa
Observed MW: 66 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ESR1 (pS106) Antibody

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