ESR1 (pS106) Antibody
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Catalogue No: abx000395
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US$232.00
(Size: 20 µl)
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Datasheet SDS
ESR1 (pS106) Antibody is a Rabbit Polyclonal antibody against ESR1 (pS106). This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Research Articles on ESR1 (pS106)
| Target | ESR1 (pS106) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S106 of human Estrogen Receptor alpha (ESR1) |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P03372 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7 |
| UniProt Entry Name | ESR1_HUMAN |
| Gene Symbol | ESR1 |
| GeneID | 2099 |
| KEGG | hsa:2099 |
| String | 9606.ENSP00000405330 |
| Molecular Weight | Calculated MW: 66 kDa Observed MW: 66 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |