Estrogen Receptor Beta (ESR2) Antibody
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Catalogue No: abx025483
Price:
US$623.50
(Size: 100 µl)
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Datasheet SDS
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. This antibody is supplied as crude ascites.
Research Articles on Estrogen Receptor Beta (ESR2)
| Target | Estrogen Receptor Beta (ESR2) |
| Research Area | Endocrinology, Reproductive Science, Hormone Metabolism |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 369-397 amino acids from the Central region of human ESR2. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q92731 (UniProt, ExPASy) |
| Molecular Weight | Calculated MW: 59.2 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Cow, Pig, Chicken and Sheep ESR2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |