ETS Translocation Variant 6 (ETV6) Antibody

ETV6 Antibody is a Rabbit Polyclonal antibody against ETV6. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008].

Target	ETS Translocation Variant 6 (ETV6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41212 (UniProt, ExPASy)
UniProt Secondary AC	A3QVP6, A8K076, Q9UMF6, Q9UMF7, Q9UMG0
UniProt Entry Name	ETV6_HUMAN
Gene Symbol	ETV6
GeneID	2120
NCBI Accession	NP_001978.1
KEGG	hsa:2120
String	9606.ENSP00000379658
Molecular Weight	Calculated MW: 53 kDa Observed MW: 53 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ETS Translocation Variant 6 (ETV6)

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