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Junctional Adhesion Molecule 1 / JAM1 (F11R) Antibody

Catalogue No: abx001153
Price: £120.00
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Junctional Adhesion Molecule 1 / JAM1 (F11R) Antibody

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F11R Antibody is a Rabbit Polyclonal antibody against F11R. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Target Junctional Adhesion Molecule 1 / JAM1 (F11R)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human F11R.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y624 (UniProt, ExPASy)
UniProt Secondary AC B7Z941
UniProt Entry Name JAM1_HUMAN
Gene Symbol F11R
GeneID 50848
String 9606.ENSP00000357005
Molecular Weight Calculated MW: 27 kDa, 32 kDa
Observed MW: 40 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Junctional Adhesion Molecule 1 / JAM1 (F11R) Antibody

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