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Coagulation Factor III, Tissue Factor / CD142 (F3) Antibody

Catalogue No: abx001211
Price: £120.00
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Coagulation Factor III, Tissue Factor / CD142 (F3) Antibody Coagulation Factor III, Tissue Factor / CD142 (F3) Antibody

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F3 Antibody is a Rabbit Polyclonal antibody against F3. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

Target Coagulation Factor III, Tissue Factor / CD142 (F3)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human F3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P13726 (UniProt, ExPASy)
UniProt Secondary AC D3DT47, Q6FHG2, Q86WH4
UniProt Entry Name TF_HUMAN
Gene Symbol F3
GeneID 2152
String 9606.ENSP00000334145
Molecular Weight Calculated MW: 27 kDa, 33 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Coagulation Factor III, Tissue Factor / CD142 (F3) Antibody

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