Coagulation Factor IX (F9) Antibody

F9 Antibody is a Rabbit Polyclonal antibody against F9. This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq, Jul 2008].

Target	Coagulation Factor IX (F9)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human Factor IX / F9.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P00740 (UniProt, ExPASy)
UniProt Secondary AC	A8K9N4, F2RM36, Q5FBE1, Q5JYJ8
UniProt Entry Name	FA9_HUMAN
Gene Symbol	F9
GeneID	2158
NCBI Accession	NP_000124.1
KEGG	hsa:2158
String	9606.ENSP00000218099
Molecular Weight	Calculated MW: 52 kDa Observed MW: 52/66 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Coagulation Factor IX (F9)

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