Protein FAM3B (FAM3B) Antibody

FAM3B Antibody is a Rabbit Polyclonal antibody against FAM3B. FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.

Target	Protein FAM3B (FAM3B)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	IHC, IF/ICC
Host	Rabbit
Recommended dilutions	IHC-P: 1/100 - 1/200, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P58499 (UniProt, ExPASy)
UniProt Entry Name	FAM3B_HUMAN
Gene Symbol	FAM3B
GeneID	54097
NCBI Accession	NP_478066.3
KEGG	hsa:54097
String	9606.ENSP00000350673
Molecular Weight	Calculated MW: 26 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein FAM3B (FAM3B)

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