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Protein FAM3B (FAM3B) Antibody

Catalogue No: abx001005
Price: £120.00
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Protein FAM3B (FAM3B) Antibody Protein FAM3B (FAM3B) Antibody

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FAM3B Antibody is a Rabbit Polyclonal antibody against FAM3B. FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.

Target Protein FAM3B (FAM3B)
Clonality Polyclonal
Reactivity Human
Tested Applications IHC
Host Rabbit
Recommended dilutions IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FAM3B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P58499 (UniProt, ExPASy)
UniProt Entry Name FAM3B_HUMAN
Gene Symbol FAM3B
GeneID 54097
KEGG hsa:5409
String 9606.ENSP00000350673
Molecular Weight Calculated MW: 20 kDa, 25 kDa, 30 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein FAM3B (FAM3B) Antibody

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