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Fanconi Anemia Group I Protein (FANCI) Antibody
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Catalogue No: abx002475
Price:
US$203.00
(Size: 20 µl)
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Fanconi Anemia Group I Protein (FANCI) Antibody is a Rabbit Polyclonal antibody against Fanconi Anemia Group I Protein (FANCI). The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, Fanconi Anemia Group I Protein (FANCI), FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
Research Articles on Fanconi Anemia Group I Protein (FANCI)
| Target | Fanconi Anemia Group I Protein (FANCI) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1061-1328 of human FANCI. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NVI1 (UniProt, ExPASy) |
| UniProt Secondary AC | A4ZVE4, A5YMH4, A6NJZ0, Q96JN1, Q96ST0, Q9BT96 |
| UniProt Entry Name | FANCI_HUMAN |
| Gene Symbol | FANCI |
| GeneID | 55215 |
| NCBI Accession | NP_001106849.1 |
| String | 9606.ENSP00000310842 |
| Molecular Weight | Calculated MW: 149 kDa Observed MW: 149 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
