Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG) Antibody
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Catalogue No: abx000619
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US$217.50
(Size: 20 µl)
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Datasheet SDS
FasLG Antibody is a Rabbit Polyclonal antibody against FasLG. This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Research Articles on Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG)
| Target | Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG) |
| Research Area | Apoptosis, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to FasLG. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P48023 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9BZP9 |
| UniProt Entry Name | TNFL6_HUMAN |
| Gene Symbol | FASLG |
| GeneID | 356 |
| NCBI Accession | NP_000630.1 |
| KEGG | hsa:356 |
| String | 9606.ENSP00000356694 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 41 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |