Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG) Antibody

FasLG Antibody is a Rabbit Polyclonal antibody against FasLG. This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Target	Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 101-200 of human FasLG.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P48023 (UniProt, ExPASy)
UniProt Secondary AC	Q9BZP9
UniProt Entry Name	TNFL6_HUMAN
Gene Symbol	FASLG
GeneID	356
NCBI Accession	NP_000630.1
KEGG	hsa:356
String	9606.ENSP00000356694
Molecular Weight	Calculated MW: 31 kDa Observed MW: 41 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Ligand Superfamily Member 6 (FasLG)

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