Fas Activated Serine/Threonine Kinase (FASTK) Antibody

FASTK Antibody is a Rabbit Polyclonal antibody against FASTK. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Target	Fas Activated Serine/Threonine Kinase (FASTK)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 360-549 of human FASTK.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14296 (UniProt, ExPASy)
UniProt Secondary AC	A8K867, F8VTW9, Q59EM8, Q8IVA0
UniProt Entry Name	FASTK_HUMAN
Gene Symbol	FASTK
GeneID	10922
NCBI Accession	NP_006703.1
KEGG	hsa:10922
String	9606.ENSP00000297532
Molecular Weight	Calculated MW: 61 kDa Observed MW: 61 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fas Activated Serine/Threonine Kinase (FASTK)

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