F-Box/LRR-Repeat Protein 2 (FBXL2) Antibody

FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.

Target	F-Box/LRR-Repeat Protein 2 (FBXL2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 366-395 amino acids from the C-terminal region of human FBXL2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UKC9 (UniProt, ExPASy)
UniProt Secondary AC	B4DQV0, E9PD06, Q6IAN3, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9
UniProt Entry Name	FBXL2_HUMAN
Gene Symbol	FBXL2
String	9606.ENSP00000417601
Molecular Weight	Calculated MW: 47.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse FBXL2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on F-Box/LRR-Repeat Protein 2 (FBXL2)

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