F-Box Protein 32 (FBXO32) Antibody

FBXO32 Antibody is a Rabbit Polyclonal antibody against FBXO32. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	F-Box Protein 32 (FBXO32)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q969P5 (UniProt, ExPASy)
UniProt Secondary AC	A4KYM0
UniProt Entry Name	FBX32_HUMAN
Gene Symbol	FBXO32
GeneID	114907
NCBI Accession	NP_478136.1
KEGG	hsa:114907
String	9606.ENSP00000428205
Molecular Weight	Calculated MW: 42 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on F-Box Protein 32 (FBXO32)

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