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F-Box Protein 8 (FBXO8) Antibody
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Catalogue No: abx030520
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor (s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Research Articles on F-Box Protein 8 (FBXO8)
| Target | F-Box Protein 8 (FBXO8) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 168-195 amino acids from the Central region of human FBXO8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NRD0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RB40, D3DP41, G5E9Z0, Q6UWN4, Q8IWE1, Q9NRP5, Q9UKC4 |
| UniProt Entry Name | FBX8_HUMAN |
| Gene Symbol | FBXO8 |
| String | 9606.ENSP00000377280 |
| Molecular Weight | Calculated MW: 37.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow FBXO8. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |