F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
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Catalogue No: abx025658
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Research Articles on F-Box And WD Repeat Domain Containing 12 (FBXW12)
| Target | F-Box And WD Repeat Domain Containing 12 (FBXW12) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q6X9E4 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PG36, Q494Y9, Q494Z0 |
| UniProt Entry Name | FBW12_HUMAN |
| Gene Symbol | FBXW12 |
| KEGG | hsa:285231 |
| String | 9606.ENSP00000296438 |
| Molecular Weight | Calculated MW: 53.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |