Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody

Catalogue No: abx001989
Price: £120.00
(Size: 20 µl)
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FCGR3A Antibody is a Rabbit Polyclonal antibody against FCGR3A. This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FCGR3A.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08637 (UniProt, ExPASy)
UniProt Secondary AC A2N6W9, Q53FJ0, Q53FL6, Q5EBR4, Q65ZM6, Q6PIJ0
Gene Symbol FCGR3A
GeneID 2214
Molecular Weight Calculated MW: 29 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A)

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