Fibrinogen Beta (FGB) Antibody

FGB Antibody is a Rabbit Polyclonal antibody against FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Jul 2008].

Target	Fibrinogen Beta (FGB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 111-222 of human FGB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02675 (UniProt, ExPASy)
UniProt Secondary AC	A0JLR9, B2R7G3, Q32Q65, Q3KPF2
UniProt Entry Name	FIBB_HUMAN
Gene Symbol	FGB
GeneID	2244
NCBI Accession	NP_005132.2
KEGG	hsa:2244
String	9606.ENSP00000306099
Molecular Weight	Calculated MW: 56 kDa Observed MW: 56 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fibrinogen Beta (FGB)

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