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Fibrinogen Beta (FGB) Antibody

Catalogue No: abx001220
Price: £120.00
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FGB Antibody is a Rabbit Polyclonal antibody against FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Jul 2008].

Target Fibrinogen Beta (FGB)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FGB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P02675 (UniProt, ExPASy)
UniProt Secondary AC A0JLR9, B2R7G3, Q32Q65, Q3KPF2
UniProt Entry Name FIBB_HUMAN
Gene Symbol FGB
GeneID 2244
KEGG hsa:224
String 9606.ENSP00000306099
Molecular Weight Calculated MW: 55 kDa
Observed MW: 56 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fibrinogen Beta (FGB) Antibody

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