Fibroblast Growth Factor 2 (FGF2) Antibody
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Catalogue No: abx010777
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US$427.75
(Size: 100 µl)
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Datasheet SDS
FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of anguogenesis. Due to its basic pH, the factor is also basic FGF (bFGF). Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FGF1).
Research Articles on Fibroblast Growth Factor 2 (FGF2)
| Target | Fibroblast Growth Factor 2 (FGF2) |
| Research Area | Cytokines, Tumor Immunity, Infection Immunity, Cardiovascular Biology, Cancer |
| Clonality | Monoclonal |
| Clone | G152 |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of FGF2 expressed in E. coli |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P09038 (UniProt, ExPASy) |
| UniProt Entry Name | FGF2_HUMAN |
| Gene Symbol | FGF2 |
| GeneID | 2247 |
| OMIM | 134920 |
| NCBI Accession | NP_001997.5 NM_002006.4 |
| HGNC | 3676 |
| KEGG | hsa:2247 |
| Ensembl | ENSG00000138685 |
| String | 9606.ENSP00000264498 |
| Molecular Weight | 31 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |