Fibroblast Growth Factor 2 (FGF2) Antibody

Fibroblast Growth Factor 2 (FGF2) Antibody is a Rabbit Polyclonal antibody against Fibroblast Growth Factor 2 (FGF2). The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Target	Fibroblast Growth Factor 2 (FGF2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 143-288 of human FGF2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P09038 (UniProt, ExPASy) P15655 (UniProt, ExPASy) P13109 (UniProt, ExPASy)
UniProt Entry Name	FGF2_HUMAN, FGF2_MOUSE, FGF2_RAT
Gene Symbol	FGF2
GeneID	2247 14173 54250
OMIM	134920
NCBI Accession	NP_001997.5 NM_002006.4
HGNC	3676
Ensembl	ENSG00000138685, ENSMUSG00000037225, ENSRNOG00000017392
String	9606.ENSP00000264498 10090.ENSMUSP00000037694 10116.ENSRNOP00000023388
Molecular Weight	Calculated MW: 31 kDa Observed MW: 26 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fibroblast Growth Factor 2 (FGF2)

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