Tyrosine-Protein Kinase Fgr (FGR) Antibody
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Catalogue No: abx001690
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US$348.00
(Size: 60 µl)
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Datasheet SDS
FGR Antibody is a Rabbit Polyclonal antibody against FGR. This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Research Articles on Tyrosine-Protein Kinase Fgr (FGR)
| Target | Tyrosine-Protein Kinase Fgr (FGR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human FGR |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P09769 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPL7, Q9UIQ3 |
| UniProt Entry Name | FGR_HUMAN |
| Gene Symbol | FGR |
| GeneID | 2268 |
| NCBI Accession | NP_005239.1 |
| KEGG | hsa:2268 |
| String | 9606.ENSP00000363117 |
| Molecular Weight | Calculated MW: 59 kDa Observed MW: 53 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
