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Tyrosine-Protein Kinase Fgr (FGR) Antibody

Catalogue No: abx001690
Price: £120.00
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Tyrosine-Protein Kinase Fgr (FGR) Antibody

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FGR Antibody is a Rabbit Polyclonal antibody against FGR. This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target FGR
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human FGR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P09769 (UniProt, ExPASy)
UniProt Secondary AC D3DPL7, Q9UIQ3
UniProt Entry Name FGR_HUMAN
Gene Symbol FGR
GeneID 2268
KEGG hsa:2268
String 9606.ENSP00000363117
Molecular Weight Calculated MW: 59 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tyrosine-Protein Kinase Fgr (FGR) Antibody

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