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Fragile Histidine Triad (FHIT) Antibody

Catalogue No: abx001109
Price: £120.00
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Fragile Histidine Triad (FHIT) Antibody Fragile Histidine Triad (FHIT) Antibody Fragile Histidine Triad (FHIT) Antibody

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FHIT Antibody is a Rabbit Polyclonal antibody against FHIT. This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].

Target FHIT
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FHIT.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49789 (UniProt, ExPASy)
UniProt Secondary AC A2IAS9, A2IAT0, A2IAT6, A8K1A9, Q45QG9, Q6IU12
UniProt Entry Name FHIT_HUMAN
Gene Symbol FHIT
GeneID 2272
KEGG hsa:2272
String 9606.ENSP00000417480
Molecular Weight Calculated MW: 16 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fragile Histidine Triad (FHIT) Antibody

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