Fibulin 5 (FBLN5) Antibody
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Catalogue No: abx015748
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Fibulin 5 (FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo.Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres.Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly.Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.
Research Articles on Fibulin 5 (FBLN5)
| Target | Fibulin 5 (FBLN5) |
| Research Area | Developmental Science |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of Fibulin 5 expressed in E. coli. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UBX5 (UniProt, ExPASy) |
| UniProt Secondary AC | O75966, Q6IAL4, Q6UWA3 |
| UniProt Entry Name | FBLN5_HUMAN |
| Gene Symbol | FBLN5 |
| GeneID | 10516 |
| OMIM | 219100 |
| HGNC | 3602 |
| Ensembl | ENSG00000140092 |
| String | 9606.ENSP00000345008 |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |