FK-506

FK-506, also known as Fujimycin or Tacrolimus, is a small molecule which can act as a FKBP inhibitor. It is provided as a white powder.

It is a macrolide that prevents the dephosphorylation of NF-AT, and reduces peptidyl-prolyl isomerase activity by binding to FKBP12, creating a new complex that interacts with and inhibits calcineurin.

This product acts on the following target types: Immunophilin, Phosphatase, Antibiotic.
This product acts on the following biochemical pathways: Proliferation, Cell cycle, Mtor.
This product may be of interest in the following research areas and diseases: Immunology, Infectious disease.
This product may act as a Coronavirus inhibitor: mTORC1 pathway members interact with SARS-CoV-2 N and Orf8 proteins.

Please note that our chemical products are for scientific research use only in a laboratory and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.

Target	FK-506
Form	Solid
Purity	> 98%
Reconstitution	Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
Storage	Store desiccated at -20 °C for up to 1 year. Solutions can be stored at -20 °C for up to 1 month.
Molecular Weight	804 g/mol
Molecular Formula	C44H69NO12
Buffer	Not applicable.
CAS Number	104987-11-3
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on FK-506

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