FK506 Binding Protein 5 (FKBP5) Antibody

FKBP5 Antibody is a Rabbit Polyclonal antibody against FKBP5. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Target	FK506 Binding Protein 5 (FKBP5)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 308-457 of human FKBP51/FKBP5.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13451 (UniProt, ExPASy)
UniProt Secondary AC	F5H7R1, Q59EB8, Q5TGM6
UniProt Entry Name	FKBP5_HUMAN
GeneID	2289
NCBI Accession	NP_001139247.1
KEGG	hsa:2289
String	9606.ENSP00000444810
Molecular Weight	Calculated MW: 51 kDa Observed MW: 51 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on FK506 Binding Protein 5 (FKBP5)

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