FK506 Binding Protein 1A (FKBP1A) Antibody

Catalogue No: abx001462
Price: £120.00
(Size: 20 µl)
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FKBP1A Antibody is a Rabbit Polyclonal antibody against FKBP1A. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008].

Target FKBP1A
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FKBP1A.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62942 (UniProt, ExPASy)
UniProt Secondary AC D3DVW6, P20071, Q4VC47, Q6FGD9, Q6LEU3, Q9H103, Q9H566
UniProt Entry Name FKB1A_HUMAN
Gene Symbol FKBP1A
GeneID 2280
KEGG hsa:2280
String 9606.ENSP00000383003
Molecular Weight Calculated MW: 11 kDa
Observed MW: 12 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on FK506 Binding Protein 1A (FKBP1A) Antibody

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