FK506 Binding Protein 1A (FKBP1A) Antibody
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Catalogue No: abx001462
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US$348.00
(Size: 60 µl)
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Datasheet SDS
FKBP1A Antibody is a Rabbit Polyclonal antibody against FKBP1A. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008].
Research Articles on FK506 Binding Protein 1A (FKBP1A)
| Target | FK506 Binding Protein 1A (FKBP1A) |
| Research Area | Immunology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human FKBP1A |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P62942 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVW6, P20071, Q4VC47, Q6FGD9, Q6LEU3, Q9H103, Q9H566 |
| UniProt Entry Name | FKB1A_HUMAN |
| Gene Symbol | FKBP1A |
| GeneID | 2280 |
| NCBI Accession | NP_000792.1 |
| KEGG | hsa:2280 |
| String | 9606.ENSP00000383003 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
