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Vascular Endothelial Growth Factor Receptor 1 (FLT1) Antibody

Catalogue No: abx000538
Price: £120.00
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FLT1 Antibody is a Rabbit Polyclonal antibody against FLT1. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Target FLT1
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FLT1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17948 (UniProt, ExPASy)
Gene Symbol FLT1
GeneID 2321
Molecular Weight Calculated MW: 39 kDa, 41 kDa, 52- 82 kDa, 150 kDa
Observed MW: 43 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 2.64 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Vascular Endothelial Growth Factor Receptor 1 (FLT1) Antibody

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