Vascular Endothelial Growth Factor Receptor 1 (FLT1) Antibody

FLT1 Antibody is a Rabbit Polyclonal antibody against FLT1. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Target	Vascular Endothelial Growth Factor Receptor 1 (FLT1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1180 of human VEGFR1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17948 (UniProt, ExPASy)
Gene Symbol	FLT1
GeneID	2321
NCBI Accession	NP_002010.2
Molecular Weight	Calculated MW: 151 kDa Observed MW: 200 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	2.64 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Vascular Endothelial Growth Factor Receptor 1 (FLT1)

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