Flavin Containing Monooxygenase 2 (FMO2) Antibody

FMO2 Antibody is a Rabbit Polyclonal antibody against FMO2. The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in some human populations, this enzyme is truncated and likely degraded rapidly. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

Target	Flavin Containing Monooxygenase 2 (FMO2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 210-470 of human FMO2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99518 (UniProt, ExPASy)
UniProt Secondary AC	Q5EBX4, Q86U73, Q9BRX1
UniProt Entry Name	FMO2_HUMAN
Gene Symbol	FMO2
GeneID	2327
NCBI Accession	NP_001451.2
KEGG	hsa:2327
String	9606.ENSP00000209929
Molecular Weight	Calculated MW: 61 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Flavin Containing Monooxygenase 2 (FMO2)

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