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Fragile X Mental Retardation 1 (FMR1) Antibody
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Catalogue No: abx010789
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US$427.75
(Size: 100 µl)
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Datasheet SDS
FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
Research Articles on Fragile X Mental Retardation 1 (FMR1)
| Target | Fragile X Mental Retardation 1 (FMR1) |
| Research Area | Metabolism |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human FMR1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q06787 (UniProt, ExPASy) |
| UniProt Entry Name | FMR1_HUMAN |
| Gene Symbol | FMR1 |
| GeneID | 2332 |
| OMIM | 300623 |
| HGNC | 3775 |
| KEGG | hsa:2332 |
| Ensembl | ENSG00000102081 |
| String | 9606.ENSP00000359506 |
| Molecular Weight | 71 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |