Proto-Oncogene C-Fos (FOS) Antibody
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Catalogue No: abx000621
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US$217.50
(Size: 20 µl)
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Datasheet SDS
FOS Antibody is a Rabbit Polyclonal antibody against FOS. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Research Articles on Proto-Oncogene C-Fos (FOS)
| Target | Proto-Oncogene C-Fos (FOS) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to FOS. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01100 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4E2, B4DQ65, P18849 |
| UniProt Entry Name | FOS_HUMAN |
| Gene Symbol | FOS |
| GeneID | 2353 |
| NCBI Accession | NP_005243.1 |
| KEGG | hsa:2353 |
| String | 9606.ENSP00000306245 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 55-60 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
