Forkhead Box Protein O3 (FOXO3) Antibody
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Catalogue No: abx027330
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Research Articles on Forkhead Box Protein O3 (FOXO3)
| Target | Forkhead Box Protein O3 (FOXO3) |
| Research Area | Signal Transduction, Tumor Immunity, Immunology, Developmental Science, Autoimmunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FOXO3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43524 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DVZ6, E1P5E6, O15171, Q5T2I7, Q9BZ04 |
| UniProt Entry Name | FOXO3_HUMAN |
| Gene Symbol | FOXO3 |
| NCBI Accession | NP_001446.1 NP_963853.1 |
| KEGG | hsa:2309 |
| String | 9606.ENSP00000385824 |
| Molecular Weight | Calculated MW: 71.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse FOXO3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |