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Forkhead Box Protein P3 (FOXP3) Antibody
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Catalogue No: abx010805
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Research Articles on Forkhead Box Protein P3 (FOXP3)
| Target | Forkhead Box Protein P3 (FOXP3) |
| Research Area | Signal Transduction, Apoptosis, Tumor Immunity, Infection Immunity, Immunology, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human FOXP3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9BZS1 (UniProt, ExPASy) |
| UniProt Secondary AC | A5HJT1, B7ZLG0, B9UN80, O60827, Q14DD8, Q4ZH51 |
| UniProt Entry Name | FOXP3_HUMAN |
| Gene Symbol | FOXP3 |
| GeneID | 50943 |
| OMIM | 300292 |
| HGNC | 6106 |
| Ensembl | ENSG00000049768 |
| String | 9606.ENSP00000365380 |
| Molecular Weight | 47.2 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |