Frataxin (FXN) Antibody

Catalogue No: abx001453
Price: £120.00
(Size: 20 µl)
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FXN Antibody is a Rabbit Polyclonal antibody against FXN. FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14kd or 18kd.

Target FXN
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FXN.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q16595 (UniProt, ExPASy)
UniProt Secondary AC A8MXJ6, C9JJ89, O15545, O95656, Q15294, Q5VZ01
UniProt Entry Name FRDA_HUMAN
Gene Symbol FXN
GeneID 2395
KEGG hsa:2395
String 9606.ENSP00000366482
Molecular Weight Calculated MW: 19 kDa, 21 kDa, 23 kDa
Observed MW: 14 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on FXN

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