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Frizzled Homolog 7 (FZD7) Antibody
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Catalogue No: abx003117
Price:
US$217.50
(Size: 20 µl)
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FZD7 Antibody is a Rabbit Polyclonal antibody against FZD7. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Research Articles on Frizzled Homolog 7 (FZD7)
| Target | Frizzled Homolog 7 (FZD7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to FZD7. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75084 (UniProt, ExPASy) |
| UniProt Secondary AC | O94816, Q53S59, Q96B74 |
| UniProt Entry Name | FZD7_HUMAN |
| Gene Symbol | FZD7 |
| GeneID | 8324 |
| NCBI Accession | NP_003498.1 |
| KEGG | hsa:8324 |
| String | 9606.ENSP00000286201 |
| Molecular Weight | Calculated MW: 64 kDa Observed MW: 70-72 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |