Frizzled Homolog 7 (FZD7) Antibody

FZD7 Antibody is a Rabbit Polyclonal antibody against FZD7. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Target	Frizzled Homolog 7 (FZD7)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human FZD7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75084 (UniProt, ExPASy)
UniProt Secondary AC	O94816, Q53S59, Q96B74
UniProt Entry Name	FZD7_HUMAN
Gene Symbol	FZD7
GeneID	8324
NCBI Accession	NP_003498.1
KEGG	hsa:8324
String	9606.ENSP00000286201
Molecular Weight	Calculated MW: 64 kDa Observed MW: 70-72 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Frizzled Homolog 7 (FZD7)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue