Glucose-6-Phosphate Dehydrogenase (G6PD) Antibody
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Catalogue No: abx012126
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Glucose-6-Phosphate Dehydrogenase (G6PD)
| Target | Glucose-6-Phosphate Dehydrogenase (G6PD) |
| Research Area | Cardiovascular Biology |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human G6PD expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P11413 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DWX9, Q16000, Q16765, Q8IU70, Q8IU88, Q8IUA6, Q96PQ2 |
| UniProt Entry Name | G6PD_HUMAN |
| Gene Symbol | G6PD |
| GeneID | 2539 |
| OMIM | 300908 |
| HGNC | 4057 |
| KEGG | hsa:2539 |
| Ensembl | ENSG00000160211 |
| String | 9606.ENSP00000377192 |
| Molecular Weight | 59 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |