Glucose-6-Phosphate Dehydrogenase (G6PD) Antibody

This gene encodes glucose-6-phosphate dehydrogenase.This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions.G6PD is remarkable for its genetic diversity.Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms.G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.Two transcript variants encoding different isoforms have been found for this gene.

Target	Glucose-6-Phosphate Dehydrogenase (G6PD)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human G6PD expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11413 (UniProt, ExPASy)
UniProt Secondary AC	D3DWX9, Q16000, Q16765, Q8IU70, Q8IU88, Q8IUA6, Q96PQ2
UniProt Entry Name	G6PD_HUMAN
Gene Symbol	G6PD
GeneID	2539
OMIM	300908
HGNC	4057
KEGG	hsa:2539
Ensembl	ENSG00000160211
String	9606.ENSP00000377192
Molecular Weight	59 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glucose-6-Phosphate Dehydrogenase (G6PD)

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