Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody

Catalogue No: abx002817
Price: £120.00
(Size: 20 µl)
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Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody

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gABRA4 Antibody is a Rabbit Polyclonal antibody against gABRA4. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Target gamma Aminobutyric Acid Receptor Subunit alpha 4
Clonality Polyclonal
Reactivity Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GABRA4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48169 (UniProt, ExPASy)
UniProt Secondary AC Q8IYR7
UniProt Entry Name GBRA4_HUMAN
Gene Symbol GABRA4
GeneID 2557
KEGG hsa:2557
String 9606.ENSP00000264318
Molecular Weight Calculated MW: 61 kDa
Observed MW: 72 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody

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