Glutamate Decarboxylase 2 (GAD2) Antibody

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Catalogue No: abx112740
Price: US$710.50
(Size: 100 µl)

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Datasheet SDS
Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65Kda) Antibody is a Rabbit Polyclonal antibody against Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65Kda). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Target Glutamate Decarboxylase 2 (GAD2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Human GAD2.
Isotype IgG
Form Liquid
Purification Antigen Affinity Chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q05329 (UniProt, ExPASy) P48320 (UniProt, ExPASy) Q05683 (UniProt, ExPASy)
UniProt Secondary AC Q9UD87, O35519
UniProt Entry Name DCE2_HUMAN, DCE2_MOUSE, DCE2_RAT
Gene Symbol GAD2
GeneID 2572 14417 24380
OMIM 138275
HGNC 4093
Ensembl ENSG00000136750, ENSMUSG00000026787, ENSRNOG00000018200
String 9606.ENSP00000365437 10090.ENSMUSP00000028123 10116.ENSRNOP00000024901
Buffer PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutamate Decarboxylase 2 (GAD2)


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