Glutamate Decarboxylase 2 (GAD2) Antibody

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Catalogue No: abx016167
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Glutamate Decarboxylase 2 (GAD2) Antibody is a Mouse Monoclonal against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Target Glutamate Decarboxylase 2 (GAD2)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human GAD2 (AA: 1-100) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q05329 (UniProt, ExPASy)
UniProt Secondary AC Q9UD87
UniProt Entry Name DCE2_HUMAN
Gene Symbol GAD2
GeneID 2572
OMIM 138275
NCBI Accession NM_000818.2 NM_001134366.1
HGNC 4093
KEGG hsa:2572
Ensembl ENSG00000136750
String 9606.ENSP00000365437
Molecular Weight 65.4 kDa
Buffer PBS, containing 0.05% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutamate Decarboxylase 2 (GAD2)


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