Glutamate Decarboxylase 2 (GAD2) Antibody (HRP)

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Catalogue No: abx317297
Price: US$188.50
(Size: 20 µg)

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Datasheet SDS
Glutamate Decarboxylase 2 (GAD2) Antibody (HRP) is a Rabbit Polyclonal against Glutamate Decarboxylase 2 (GAD2) conjugated to HRP. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Target Glutamate Decarboxylase 2 (GAD2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation HRP
Immunogen Recombinant Human Glutamate decarboxylase 2 protein (1-82AA).
Isotype IgG
Form Liquid
Purity > 95%
Purification Purified by Protein G.
Storage Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q05329 (UniProt, ExPASy)
UniProt Secondary AC Q9UD87
UniProt Entry Name DCE2_HUMAN
Gene Symbol GAD2
GeneID 2572
OMIM 138275
NCBI Accession NM_000818.2 NM_001134366.1
HGNC 4093
KEGG hsa:2572
Ensembl ENSG00000136750
String 9606.ENSP00000365437
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutamate Decarboxylase 2 (GAD2)


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