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DNA Damage Inducible Transcript 3 (DDIT3) Antibody
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Catalogue No: abx010559
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US$348.00
(Size: 50 µl)
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Datasheet SDS
GADD153 Antibody detects endogenous levels of GADD153. CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.
Research Articles on DNA Damage Inducible Transcript 3 (DDIT3)
| Target | DNA Damage Inducible Transcript 3 (DDIT3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthesised peptide derived from human GADD153 |
| Form | Liquid |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35638 (UniProt, ExPASy) |
| UniProt Secondary AC | F8VS99 |
| UniProt Entry Name | DDIT3_HUMAN |
| Gene Symbol | DDIT3 |
| GeneID | 1649 |
| OMIM | 126337 |
| HGNC | 2726 |
| KEGG | hsa:1649 |
| Ensembl | ENSG00000175197 |
| String | 9606.ENSP00000448665 |
| Molecular Weight | 26 kDa |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Specificity | GADD153 Antibody detects endogenous levels of GADD153 |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |