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DNA Damage Inducible Transcript 3 (DDIT3) Cell ELISA Kit
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Catalogue No: abx595638
Price:
US$572.75
(Size: 96 tests)
Orders to United States ship from United States
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GADD153 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Research Articles on DNA Damage Inducible Transcript 3 (DDIT3)
| Introduction | GADD153 (also know as DNA Damage Inducible Transcript 3, DDIT3, and C/EBP homologous protein, CHOP) is a transcription factor that induces the production of various pro-apoptotic proteins and cytokines, while repressing some anti-apoptotic proteins. DDIT3 is upregulated during endoplasmic reticulum stress, and is frequently used as a biomarker of this process. Mice deficient in DDIT3 were less likely to generate an inflammatory response in the lungs when administered LPS. |
| Target | DNA Damage Inducible Transcript 3 (DDIT3) |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Validity | 6 months. |
| UniProt Primary AC | P35638 (UniProt, ExPASy) |
| UniProt Secondary AC | F8VS99 |
| UniProt Entry Name | DDIT3_HUMAN |
| Gene Symbol | DDIT3 |
| GeneID | 1649 |
| OMIM | 126337 |
| HGNC | 2726 |
| KEGG | hsa:1649 |
| Ensembl | ENSG00000175197 |
| String | 9606.ENSP00000448665 |
| Detection Method | Colorimetric |
| Plate Coating | Uncoated |
| Substrate | TMB |
| Detection Antibody Conjugation | HRP |
| Availability | Shipped within 1-2 weeks. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |